Proteasome inhibition by bortezomib parallels a reduction in head and neck cancer cells growth, and an increase in tumor-infiltrating immune cells
M Benvenuto, S Ciuffa, C Focaccetti, D Sbardella… - Scientific reports, 2021 - nature.com
… SALTO-5 cells. Our findings further support the use of Bortezomib for the treatment of HNC
and … pathways in HNC cell lines when resistance to proteasome inhibition is developed. …
and … pathways in HNC cell lines when resistance to proteasome inhibition is developed. …
A novel and effective inhibitor combination involving bortezomib and OTSSP167 for breast cancer cells in light of label-free proteomic analysis
E Okur, A Yerlikaya - Cell Biology and Toxicology, 2019 - Springer
… by the combination of proteasome inhibitor bortezomib and calcium (Ca 2+ ) chelator BAPTA…
following exposure of 4T1 breast cancer cells to low concentrations of bortezomib (10 nM) …
following exposure of 4T1 breast cancer cells to low concentrations of bortezomib (10 nM) …
Exploring the time-dependent regulatory potential of microRNAs in breast cancer cells treated with proteasome inhibitors
K Katsaraki, CK Kontos, G Ardavanis-Loukeris… - Clinical and …, 2024 - Springer
… the treatment of the four cell lines with both bortezomib and … Furthermore, the phenomenon
of time-dependent differential … -21-5p after treatment of the SK-BR-3 cell line with bortezomib, …
of time-dependent differential … -21-5p after treatment of the SK-BR-3 cell line with bortezomib, …
The ubiquitin-proteasome pathway and resistance mechanisms developed against the proteasomal inhibitors in cancer cells
A Yerlikaya, E Kanbur - Current Drug Targets, 2020 - ingentaconnect.com
… It is also an oral proteasome inhibitor and similar to bortezomib and carfilzomib, it is highly
… in response to proteasome inhibition in melanoma and breast cancer cells. Mol Biol (Mosk) …
… in response to proteasome inhibition in melanoma and breast cancer cells. Mol Biol (Mosk) …
[PDF][PDF] Proteasome inhibition in multiple myeloma: head-to-head comparison of currently available proteasome inhibitors
A Besse, L Besse, M Kraus, M Mendez-Lopez… - Cell chemical …, 2019 - cell.com
… To rule out effects of the differential cytotoxicity of the drugs, we compared the drugs at …
wt IC50 values for proteasome inhibitors bortezomib (BTZ) and carfilzomib (CFZ) in …
wt IC50 values for proteasome inhibitors bortezomib (BTZ) and carfilzomib (CFZ) in …
Cellular responses to proteasome inhibition: molecular mechanisms and beyond
N Albornoz, H Bustamante, A Soza… - … Journal of Molecular …, 2019 - mdpi.com
… cellular responses activated during proteasome inhibition with … -inclusion bodies, and
proteasome biogenesis dependent on … the proteasomal inhibitors bortezomib and NPI-0052 [144]. …
proteasome biogenesis dependent on … the proteasomal inhibitors bortezomib and NPI-0052 [144]. …
Combination of Second-Generation Proteasome Inhibitor Carfilzomib with Bortezomib in Four Different Breast Cancer Cell Lines
… cell death. This is a preliminary study aimed to show the efficiency of proteasome inhibitors
in breast cancer cells. … on the combination of proteasome inhibitors with standard therapies. …
in breast cancer cells. … on the combination of proteasome inhibitors with standard therapies. …
An investigation of the mechanisms underlying the proteasome inhibitor bortezomib resistance in PC3 prostate cancer cell line
A Yerlikaya, E Okur - Cytotechnology, 2020 - Springer
… breast cancer cells as compared to the benign solid tumors (Chen and Madura 2005).
Furthermore, numerous studies showed that proteasome inhibitor bortezomib … in many cancer cell …
Furthermore, numerous studies showed that proteasome inhibitor bortezomib … in many cancer cell …
Molecular analysis of cell survival and death pathways in the proteasome inhibitor bortezomib-resistant PC3 prostate cancer cell line
… breast and B16F10 melanoma cancer cells have differential levels of resistance to proteasome
inhibitors. … determined that 4T1 breast cancer cells are p53-mutants and that proteasome …
inhibitors. … determined that 4T1 breast cancer cells are p53-mutants and that proteasome …
[HTML][HTML] Spliced XBP1 levels determine sensitivity of multiple myeloma cells to proteasome inhibitor bortezomib independent of the unfolded protein response …
B Borjan, J Kern, N Steiner, E Gunsilius, D Wolf… - Frontiers in …, 2020 - frontiersin.org
… differentiated immunoglobulin-secreting plasma cells and … of the reversible proteasome
inhibitor bortezomib (BTZ) has … support proliferation and chemoresistance in breast cancer (31, 32…
inhibitor bortezomib (BTZ) has … support proliferation and chemoresistance in breast cancer (31, 32…